Diabetes Control and Cardiovascular Risk: ACCORD, ADVANCE, AVOID, and SANDS
نویسندگان
چکیده
منابع مشابه
Intensive Glycemic Control and the Prevention of Cardiovascular Events: Implications of the ACCORD, ADVANCE, and VA Diabetes Trials
D iabetes is defined by its association with hyperglycemia-specific microvascular complications; however, it also imparts a twoto fourfold risk of cardiovascular disease (CVD). Although microvascular complications can lead to significant morbidity and premature mortality, by far the greatest cause of death in people with diabetes is CVD. Results from randomized controlled trials have demonstrat...
متن کاملAction to Control Cardiovascular Risk in Diabetes (ACCORD) trial: design and methods.
Most patients with type 2 diabetes mellitus develop cardiovascular disease (CVD), with substantial loss of life expectancy. Nonfatal CVD contributes greatly to excess healthcare costs and decreased quality of life in patients with diabetes. The current epidemic of obesity has raised expectations that CVD associated with type 2 diabetes will become an even greater public health challenge. Despit...
متن کاملACCORD and Risk-Factor Control in Type 2 Diabetes.
Patients with type 2 diabetes mellitus without a history of myocardial infarction have the same risk of a coronary event as patients without diabetes who do have a history of myocardial infarction.1 This observation was part of the basis for the recommendation by the Adult Treatment Panel III (ATP III) of the National Cholesterol Education Program that diabetes should be considered a “coronary ...
متن کاملIntensive glycemic control in the ACCORD and ADVANCE trials.
Diabetes is associated with a reduced lifespan, largely as a consequence of cardiovascular disease.1-3 Although diabetes significantly increases the risk of cardiovascular events,1 the relative increase in events for each percent increase in glycated hemoglobin is modest.4 Microvascular complications of diabetes remain the leading causes of blindness and renal failure in the developed world and...
متن کاملGlycemia treatment strategies in the Action to Control Cardiovascular Risk in Diabetes (ACCORD) trial.
There is an independent progressive epidemiologic relation between glycemia and cardiovascular disease (CVD) events; however, whether lowering glucose levels with currently available therapies can reduce CVD events remains unknown. The Action to Control Cardiovascular Risk in Diabetes (ACCORD) trial is designed to answer this question in high-risk patients with type 2 diabetes mellitus. In ACCO...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Preventive Cardiology
سال: 2008
ISSN: 1520-037X,1751-7141
DOI: 10.1111/j.1751-7141.2008.00006.x